PrimACs will develop and use a novel high-throughput screening system with Arabidopsis seedlings in microtiter plates. Upon addition of a candidate compound and subsequent addition of a stress signal for example cell wall components of pathogens the priming capacity of the compound can be assessed by the oxygen transfer rate in individual plate wells (µRAMOS) containing Arabidopsis seedlings.
Test compounds are either synthesized within the consortium or taken from a library (ChemBridge) that contains over 505,000 handcrafted small chemical compounds. We expect the identification of novel natural, near-natural, and synthetic compounds to combat biotic and abiotic stress in plants (e.g. fungal pathogens and drought).